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    Recombinant Human Anti-EMC7 Soluble TCR (AHIII) (KIH) (CAT#: VS-0622-YF7062)

    Human TCR (AHIII) recognizes EMC7 peptide (ALWGFFPVL) in the context of HLA-A2 / HLA-A2 (T163A). Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.

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    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human testis
    Figure 1 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong granular cytoplasmic positivity in leydig cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/ihc_selected.jpg
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_8_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_7_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity: 75%-25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_6_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/10029/26312_A_8_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134153-EMC7

    Specifications

    • Host Species
    • Human
    • Target
    • EMC7
    • Epitope
    • ALWGFFPVL
    • MHC
    • HLA-A2 / HLA-A2 (T163A)
    • Clone
    • AHIII
    • Type
    • Soluble TCR (KIH)
    • TCR Expression Strategy
    • KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).

    Target

    • Alternative Names
    • ER membrane protein complex subunit 7; ALWGFFPVL

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    MHC Tetramer Products for Cancer
    CAT Product Name Application Type
    MHC-LC1088 PE-A*02:01/Human EMC7 (ALWGFFPVL) MHC Tetramer FCM
    MHC-LC1089 APC-A*02:01/Human EMC7 (ALWGFFPVL) MHC Tetramer FCM
    MHC-LC1090 BV421-A*02:01/Human EMC7 (ALWGFFPVL) MHC Tetramer FCM

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