Recombinant Human Anti-MART1 Soluble TCR (ZIP-Fos/ZIP-Jun) (VS-0622-YF215)
CAT#: VS-0622-YF215
Human TCR recognizes MART1 peptide (AAGIGILTV) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR. Please note that the activity is not guaranteed.
Gene Expression
Normal Tissue
Figure 1 High expression in skin 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48662/167996_B_8_1_val_selected.jpg
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Specifications
- Host Species
- Human
- Target
- MART1
- Species Reactivity
- Human
- Epitope
- AAGIGILTV
- MHC
- HLA-A2
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Melanoma
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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