Human Anti-SARS-CoV-2 RBD (clone II62) scFv-Fc Chimera
CAT#: VS-0125-FY108
The anti-scFv-Fc targeting the RBD of SARS-CoV-2 has the potential to prevent viral cell invasion. It is cloned from a specific phage library and primarily functions through competitive binding in the process of interacting with ACE2. The expression cells are typically chosen to be mammalian cells to ensure the proper folding and functionality of the antibody.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- SARS-CoV-2 Virus
- Clone
- II62
- Applications
- Inhibition
- Related Disease
- SARS-coronavirus 2 (CoV-2) infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Anti-scFv-Fc can specifically bind to the RBD of SARS-CoV-2 and participate in the inhibition of the binding between RBD and ACE2, likely through competitive binding. Therefore, it may play an important role in neutralizing viral infection, especially in preventing the virus from entering cells through ACE2.
Target
- Alternative Names
- S glycoprotein, Spike protein, Spike (S) protein
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY45 | Human Anti-SARS-CoV-2 RBD (clone S15) scFv-Fc Chimera | Neut | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
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| VS-0525-YC11 | Recombinant Anti-SARS-CoV-2 RBD Biparatopic Antibody, Symmetric IgG-sdAb | ELISA, Neut, SPR | Symmetric IgG-sdAb |
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