Recombinant Mouse Anti-MAGEA9 Soluble TCR (A31C2-B32G7) (C-Cys) (CAT#: VS-0622-YF3201)
Mouse TCR (A31C2-B32G7) recognizes MAGEA9 peptide (KVAELVHFL) in the context of HLA-A*0201. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45401/1558_H4_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45401/1558_H4_1_selected.jpg
Figure 2 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51687/1541_B4_1_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51687/1541_B4_1_selected.jpg
Figure 3 RNA cell line category: Group enriched (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123584-MAGEA9
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123584-MAGEA9
Specifications
- Host Species
- Mouse
- Target
- MAGEA9
- Species Reactivity
- Human
- Epitope
- KVAELVHFL
- MHC
- HLA-A*0201
- Clone
- A31C2-B32G7
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Melanoma
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
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MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC3194 | PE-A*02:01/Human MAGEA9 (KVAELVHFL) MHC Tetramer | FCM | |
| MHC-YF540 | A*02:01/Human MAGEA9 (ALSVMGVYV) MHC Pentamer | FCM |
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