Mouse TCR recognizes PLXNA4 peptide (FVDDLFETIF) in the context of HLA-DPA1*01:03/DPB1*02:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR. Please note that the activity is not guaranteed.

Specifications

Host Species
Mouse

Target
PLXNA4

Species Reactivity
Human

Epitope
FVDDLFETIF

MHC
HLA-DPA1*01:03/DPB1*02:01

Type
Soluble TCR (ZIP-Fos/ZIP-Jun)

Related Disease
Chronic Beryllium Disease

TCR Expression Strategy
ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

Target

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