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    Recombinant Anti-CD3E Vesicular Antibody, EV Displayed (VS-0425-YC355)

    CAT#: VS-0425-YC355

    The Recombinant Anti-CD3E Vesicular Antibody, EV Displayed (VS-0425-YC355) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD3E-expressed cells or tissues. The CD3E is a signaling molecule that is part of the immune pathways, linked to immunodeficiencies like Severe Combined Immunodeficiency.

    Gene Expression
    ❮
    Figure 1 IF staining of human cell line JURKAT Figure 2 Lymph node Figure 3 RNA cell line category: Group enriched (JURKAT, MOLT-4)
    ❯

    Recombinant Antibody

    • Application
    • ELISA, FC, Neut, Cell-uptake
    • Product Type
    • Ab-Fc-EVs
    • Antibody Quantification (Ab/EV)
    • ~100 Ab/EV
    • Target
    • CD3E
    • Host Animal
    • Mouse
    • Antibody Isotype
    • IgG
    • Species Reactivity
    • Human
    • Expression Cell
    • Mammalian cell

    Engineered EVs

    • EV-sorting domain
    • CD63
    • Fc-binding domain
    • Protein A
    • EV Size
    • 30~150 nm
    • Producing Cell
    • HEK293F
    • Isolation Method
    • Gradient centrifugation
    • Purification
    • qEV size exclusion chromatography
    • Concentration
    • 1 x 10¹⁰
    • Size
    • 1 mL
    • Buffer
    • PBS
    • Storage
    • Store at -80°C for 12 months

    Target

    • Full Name
    • CD3 epsilon subunit of T-cell receptor complex
    • Biological Process
    • Adaptive immunity, Immunity
    • Molecular Function
    • Receptor
    • Cellular Localization
    • Endoplasmic reticulum, Plasma membrane, Golgi apparatus
    • Introduction
    • CD3E (CD3e Molecule) is a Protein Coding gene. Diseases associated with CD3E include Immunodeficiency 18 and T-B+ Severe Combined Immunodeficiency Due To Cd3delta/Cd3epsilon/Cd3zeta. Among its related pathways are G-protein signaling N-RAS regulation pathway and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and signal transducer activity.
    • Alternative Names
    • CD3-epsilon, CD3epsilon
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    Datasheet

    Datasheet - VS-0425-YC355.pdf

    MSDS

    MSDS - VS-0425-YC355.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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