Afuco™ Anti-CD3D ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-159) (CAT#: AFC-TAB-159)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD3. It is a monoclonal antibody which is used as an immunosuppressive drug. It is a humanized Fc-engineered monoclonal antibody.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line JURKAT shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71778/1970_F1_3_selected.jpg
(Immunofluorescent staining of human cell line JURKAT shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71778/1970_F1_3_selected.jpg
Figure 2 RNA cell line category: Group enriched (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167286-CD3D
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167286-CD3D
Figure 2 RNA cell line category: Group enriched (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167286-CD3D
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167286-CD3D
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Generic Name
- Teplizumab
- Related Disease
- Type 1 diabetes
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD3D; CD3d molecule, delta (CD3-TCR complex); CD3d antigen, delta polypeptide (TiT3 complex), T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3, delta chain; CD3 antigen, delta subunit;
- Gene ID
- 915
- UniProt ID
- P04234
Related Resources
Please refer to Teplizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Teplizumab.
Primary Immunodeficiency
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1284z | Mouse Anti-CD3D Recombinant Antibody (clone 21C10) | WB, ELISA | Mouse IgG1 |
| HPAB-0703-FY | Mouse Anti-CD3D Recombinant Antibody (clone AB002) | ELISA | Mouse IgG |
| HPAB-0722-FY | Mouse Anti-CD3D Recombinant Antibody (clone AB039) | ELISA | Mouse IgG |
| HPAB-0381-FY | Human Anti-CD3D Recombinant Antibody (HPAB-0381-FY) | FC, ELISA | Human IgG |
| VS3-WK1275 | Mouse Anti-CD3D Recombinant Antibody (clone AI504783) | ELISA, WB, IHC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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