Anti-Human CD3 epsilon Recombinant Antibody (TAB-245) (CAT#: TAB-245)
Recombinant monoclonal antibody to CD3 epsilon. It is an immunomodulator. It binds to CD3 epsilon.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line JURKAT
(Immunofluorescent staining of human cell line JURKAT shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40957/1970_E5_1_selected.jpg
(Immunofluorescent staining of human cell line JURKAT shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40957/1970_E5_1_selected.jpg
Figure 2 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72864/157655_A_9_8.jpg
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72864/157655_A_9_8.jpg
Figure 3 RNA cell line category: Group enriched (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198851-CD3E
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000198851-CD3E
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- WB, ELISA, FC, IP, FuncS, IF, Neut
- Related Disease
- Atherosclerosis
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Applications
- Application Notes
- The CD3E antibody has been reported in applications of WB, ELISA, FC, IP, FuncS, IF, Neut.
Target
- Alternative Names
- Foralumab;946415-64-1;CD3E;CD3e molecule, epsilon (CD3-TCR complex);CD3e antigen, epsilon polypeptide (TiT3 complex);T-cell surface glycoprotein CD3 epsilon chain;CD3-epsilon;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell antigen receptor complex, e
- Gene ID
- 916
- UniProt ID
- P07766
Related Resources
Please refer to Foralumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Foralumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H28 | Anti-Human CD3E Recombinant Antibody (Ertumaxomab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG2a / G2b |
Customer Reviews and Q&As
Customer Review
Q&As
Sarah Martinez
Great for CD3 Epsilon Studies
Great for CD3 Epsilon Studies
The Anti-Human CD3 epsilon Therapeutic Antibody (Foralumab) has been excellent for our CD3 epsilon detection assays. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
15.Oct,23
Brian Anderson
Effective in Immunoassays
Effective in Immunoassays
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for CD3 epsilon is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
05.Aug,22
Megan Thompson
Consistent High-Quality Results
Consistent High-Quality Results
This antibody has proven to be consistent and dependable in our assays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for CD3 epsilon have been particularly beneficial.
09.Sep,21
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-245, RRID: AB_3111896)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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