Afuco™ Anti-CD3E ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H52) (CAT#: AFC-TAB-H52)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from rat) antibody to Human CD3E. It is a monoclonal antibody, which is being developed for the treatment of type 1 diabetes and other autoimmune diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1 Afuco™ Anti-CD3E Recombinant Antibody, ADCC Enhanced (AFC-TAB-H52) in Flow Cytometry
Cell line transfected with CD3 was stained with Anti-CD3E Therapeutic Antibody (AFC-TAB-H52)
NC1: FITC Isotype Ctrl
FITC-CD3: FITC anti-human CD3
NC2: Human IgG1, lambda Isotype Control Antibody
NC3: Blank
AFC-TAB-H52: Afuco™ Anti-CD3E Therapeutic Antibody (Otelixizumab), ADCC Enhanced
The secondary antibody: Goat Anti-human IgG FITC
Specifications
- Host Species
- Human
- Derivation
- Humanized (from rat)
- Type
- ADCC enhanced antibody
- Specificity
- CD3E (CD3 epsilon) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF
- Conjugate
- Unconjugated
- Generic Name
- Otelixizumab
- Related Disease
- Psoriasis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain;
- Gene ID
- 916
- UniProt ID
- P07766
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Otelixizumab"
DrugMonitor™ Anti-Otelixizumab Antibody (VS-1224-YC866)Otelixizumab is a monoclonal antibody that targets and binds to CD3. It was developed to treat type 1 diabetes, psoriasis, and other autoimmune diseases such as rheumatoid arthritis. The DrugMonitor™ Anti-Otelixizumab Antibody (VS-1224-YC866) is an anti-drug antibody (ADA) against Otelixizumab. This drug-based antibody is raised in mice immunized with the Otelixizumab. The anti-Otelixizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Otelixizumab in samples.
See other products for "CD3E"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H28 | Anti-Human CD3E Recombinant Antibody (Ertumaxomab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG2a / G2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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