Anti-Human CD3E Recombinant Antibody (Visilizumab) (CAT#: TAB-420CQ)
Recombinant monoclonal antibody to CD3E. Visilizumab is a humanized monoclonal antibody that can be potentially used in the treatment of Allograft rejection, Psoriasis, Autoimmune diseases.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Anti-CD3E Recombinant Antibody (TAB-420CQ) in SDS-PAGE
SDS-PAGE analysis of TAB-420CQ in non-reduced (Lane 1) and β-mercaptoethanol-reduced (Lane 2) conditions.
Figure 2 Anti-CD3E Recombinant Antibody (TAB-420CQ) in HPLC
The purity of TAB-420CQ was greater than 95% as determined by SEC-HPLC.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- IgG2, κ
- Specificity
- Human CD3E
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Functional Studies
- Conjugate
- Unconjugated
- CAS
- 219716-33-3
- Generic Name
- Visilizumab
- UNII
- H18SKU3289
- Related Disease
- Allograft rejection, Psoriasis, Autoimmune diseases
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- CD3e Molecule, Epsilon (CD3-TCR Complex); CD3e Antigen, Epsilon Polypeptide (TiT3 Complex); T-Cell Surface Antigen T3/Leu-4 Epsilon Chain; T3E; T-Cell Antigen Receptor Complex, Epsilon Subunit Of T3; CD3e Antigen; CD3-Epsilon; IMD18; TCRE
- Gene ID
- 916
- UniProt ID
- P07766
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "visilizumab"
Anti-CD3E Recombinant Antibody (Visilizumab)Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD3 receptor. Visilizumab is a humanized monoclonal antibody. It is being investigated for use as an immunosuppressive drug in patients with ulcerative colitis and Crohn's disease.
Afuco™ Anti-CD3E ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-714)This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD3 receptor. It is a humanized monoclonal antibody. It is being investigated for use as an immunosuppressive drug in patients with ulcerative colitis and Crohn's disease.
DrugMonitor™ Anti-Visilizumab Antibody (VS-1224-YC1307)Visilizumab has been investigated for ulcerative colitis treatment. The DrugMonitor™ Anti-Visilizumab Antibody (VS-1224-YC1307) is an anti-drug antibody (ADA) against Visilizumab. This drug-based antibody is raised in mice immunized with the Visilizumab. The anti-Visilizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Visilizumab in samples.
See other products for "CD3E"
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H28 | Anti-Human CD3E Recombinant Antibody (Ertumaxomab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG2a / G2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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