Recombinant Grey hamster Anti-CD3E Antibody (17A2) (CAT#: PABX-033)

Anti-CD3E antibody is a Grey hamster antibody of IgG class that binds to an CD3E.


Specific Inquiry
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  • Published Data
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WB

Figure 1 Native structure and composition of the TCR complex expressed in γδ⁻ x hδTg T cells.

Figure 1 Native structure and composition of the TCR complex expressed in γδ⁻ x hδTg T cells.

(B) Phenylphosphate-eluted TCR complexes from WT and γδ⁻ x hδTg splenocytes were incubated with the indicated amounts of the antibodies 17A2 (anti-CD3γε) or 2C11 (anti-CD3γε/δε), and subsequently resolved by BN-PAGE. The Western blot membrane was developed with anti-CD3ξ antibodies. The number of antibody-mediated shifts of the TCR complex is indicated to the right.

Fernández-Malavé, E., Wang, N., Pulgar, M., Schamel, W. W., Alarcón, B., & Terhorst, C. (2006). Overlapping functions of human CD3δ and mouse CD3γ in αβ T-cell development revealed in a humanized CD3γ-deficient mouse. Blood, 108(10), 3420-3427.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Grey hamster
  • Derivation
  • Grey hamster
  • Type
  • IgG
  • Specificity
  • Tested positive against native Mouse CD3E
  • Species Reactivity
  • Mouse
  • Clone
  • 17A2
  • Applications
  • WB, ELISA, FuncS

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • The CD3E antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Functional Assay.

Target

  • Alternative Names
  • CD3E; CD3e molecule; epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen; epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex; epsilon subunit of T3; NI-0401

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 17A2"

See other products for "CD3E"

Rat Antibody

CAT Product Name Application Type
TAB-H28 Anti-Human CD3E Recombinant Antibody (Ertumaxomab) ELISA, FC, IP, FuncS, IF, Neut, ICC IgG2a / G2b

Humanized Antibody

CAT Product Name Application Type
TAB-714 Anti-CD3E Recombinant Antibody (Visilizumab) FuncS, IF, Neut, ELISA, FC, IP, ICC IgG2
TAB-H52 Anti-Human CD3E Recombinant Antibody (Otelixizumab) FC, IP, ELISA, Neut, FuncS, IF, WB IgG1 - lambda
TAB-420CQ Anti-Human CD3E Recombinant Antibody (Visilizumab) ELISA, IHC, FC, IP, IF, FuncS IgG2, κ

Human Antibody

CAT Product Name Application Type
TAB-245 Anti-Human CD3 epsilon Recombinant Antibody (Foralumab) WB, ELISA, FC, IP, FuncS, IF, Neut IgG1 - kappa
TAB-124CL Human Anti-CD3E Recombinant Antibody (TAB-124CL) ELISA Human IgG

Mouse Antibody

Immunotoxin

CAT Product Name Application Type
AGTO-G010E Anti-CD3E immunotoxin UCHT1 (scFv)-PE Cytotoxicity assay, Function study
AGTO-G010D Anti-CD3E immunotoxin UCHT1 (scFv)-DT Cytotoxicity assay, Function study
AGTO-L049E anti-CD3E immunotoxin UCHT1 (IgG)-PE Cytotoxicity assay, Functional assay
AGTO-L049D anti-CD3E immunotoxin UCHT1 (IgG)-DT Cytotoxicity assay, Functional assay
AGTO-L049R anti-CD3E immunotoxin UCHT1 (IgG)-RTA Cytotoxicity assay, Functional assay

Recombinant Antibody

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-245 Afuco™ Anti-CD3E ADCC Recombinant Antibody (Foralumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF ADCC enhanced antibody
AFC-TAB-H52 Afuco™ Anti-CD3E ADCC Recombinant Antibody (Otelixizumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-714 Afuco™ Anti-CD3E ADCC Recombinant Antibody (Visilizumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-019 Afuco™ Anti-CD3E ADCC Recombinant Antibody (Muromonab-Cd3), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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