Recombinant Mouse Anti-KRT14/KRT16/KRT5/KRT6A/KRT8 Antibody (VS4-CJ4)
CAT#: VS4-CJ4
This mouse anti-KRT14/KRT16/KRT5/KRT6A/KRT8 antibody is a product that recognizes human KRT14/KRT16/KRT5/KRT6A/KRT8. The immunogen of this antibody is a synthesized peptide derived from human Cytokeratin Pan. The mAb has been tested for use in ELISA, Immunohistochemistry (1:20-1:200).
Specifications
- Immunogen
- Synthesized peptide derived from human Cytokeratin Pan
- Host Species
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human KRT14/KRT16/KRT5/KRT6A/KRT8
- Species Reactivity
- Human
- Applications
- ELISA, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Immunohistochemistry (1:20-1:200).
Target
- Alternative Names
- CARD2; CK-4; CK-6C; CK-6E; CK-8; CK14; CK16; CK4; CK5; CK6A; CK6C; CK6D; CK8; CYK4; CYK8; DDD; DDD1; EBS2; EBS3; EBS4; FNEPPK; K14; K16; K1CP; K2C8; K4; K5; K6A; K6C; K6D; K8; KO; KRT14; KRT16; KRT16A; KRT5; KRT5A; KRT6A; KRT6C; KRT6D; KRT8; NEPPK; NFJ; PC1; PC3; WSN1; 58 kDa cytokeratin; CK-14; CK-16; CK-5; CK-6A; CK-6D; CK-8; cytokeratin 14; cytokeratin 16; cytokeratin 4; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-14; Cytokeratin-16; Cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Cytokeratin-8; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; focal non-epidermolytic palmoplantar keratoderma; Hom s 5; K14; K16; K5; K6A; K8; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 14, type I; keratin 16, type I; keratin 4, type II; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A, type II; keratin 6A, type II; keratin 8, type II; keratin K6h; keratin, epidermal type II, K6A; Keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 16; Keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 8; Keratin-14; Keratin-16; Keratin-5; Keratin-6A; keratin-6C; Keratin-8; pankeratin; type-II keratin Kb12; type-II keratin Kb4; Type-II keratin Kb5; Type-II keratin Kb6; Type-II keratin Kb8
- Long Name
- Keratin 14/16/5/6A/8
- Sequence Similarities
- Belongs to the intermediate filament family.
- Cellular Localization
- Cytoplasm, Intermediate filament, Keratin, Nucleus
- Post Translation Modifications
- A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus.
Ubiquitinated by the BCR(KLHL24) E3 ubiquitin ligase complex.
- Protein Refseq
- NP_000517.2
- Function
- The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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