Recombinant Mouse Anti-Marburg GP Antibody (CAN30G5) (CAT#: HPAB-0202-YJ)

This product is a recombinant mouse antibody that recognizes Marburg GP. The antibody CAN30G5 reacts with the epitope (D4, D5, D6) of Marburg GP. It is cross reactive with Wlarburg/EBOV. It is useful for the prevention and treatment of filovirus infection.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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We require custom production
  • Published Data
  • Datasheet
  • MSDS
  • COA
Neut

Fgiure 1 A bar graph showing the results of pseudovirus neutralization assays with mucin-deleted MARV GP after treatment with anti-MARV mAbs (as indicated on the x-axis).

Fgiure 1 A bar graph showing the results of pseudovirus neutralization assays with mucin-deleted MARV GP after treatment with anti-MARV mAbs (as indicated on the x-axis).

Percent infectivity is shown on the y-axis. Grp30polyAb is pooled polyclonal sera from immunized mice. NON is negative control; no antibody added.

Neut

Figure 2 A bar graph showing the results of pseudovirus neutralization assays with full-length (mucin-containing) MARV GP after treatment with anti-MARV mAbs (as indicated on the x-axis).

Figure 2 A bar graph showing the results of pseudovirus neutralization assays with full-length (mucin-containing) MARV GP after treatment with anti-MARV mAbs (as indicated on the x-axis).

Percent infectivity is shown on the y-axis. Grp30polyAb is pooled polyclonal sera from immunized mice. NON is negative control; no antibody added.

FuncS

Figure 3 A Kaplan Meier plot showing the results of assays examining in vivo protection using mice challenged with a lethal dose of mouse-adapted MARV Ravn.

Figure 3 A Kaplan Meier plot showing the results of assays examining in vivo protection using mice challenged with a lethal dose of mouse-adapted MARV Ravn.

Percent survival is shown on the y-axis.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Marburg virus
  • Species Reactivity
  • Marburg, Wlarburg, EBOV
  • Clone
  • CAN30G5
  • Applications
  • ELISA, WB, Neut, FuncS

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA, Western Blot, Neutralization, Function Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • Marburg virus GP

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
HPAB-0201-YJ Recombinant Mouse Anti-Marburg GP Antibody (CAN30G4) ELISA, WB, Neut, FuncS Mouse IgG1, κ

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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