At the forefront of our Strains & Strain Bank Establishment services, we provide comprehensive Strain Bank Passage & Storage Stability Evaluation services designed to ensure that your microbial or cell strains remain viable, genetically stable, and functional throughout their storage period. Whether you are working with bacteria, yeast, or mammalian cell lines, maintaining the stability of strains over extended passages and long-term storage is crucial for consistent performance in research, production, and therapeutic applications.

Our services are backed by deep scientific expertise, advanced technologies, and a commitment to ensuring the long-term viability of strains under various conditions. We offer a complete suite of evaluation services, including passage stability monitoring, storage condition optimization, and stability testing, to guarantee that your strains are preserved in an optimal, reproducible state.

Strain Bank Passage and Storage Stability Evaluation Service at Creative Biolabs

Strain banks are essential for preserving valuable biological materials, and maintaining strain quality over time requires rigorous evaluation and monitoring. Our Strain Bank Passage & Storage Stability Evaluation service focuses on assessing the genetic and phenotypic stability of strains during serial passaging and under various storage conditions. By evaluating factors such as growth rate, morphology, genetic integrity, and productivity, we ensure that strains remain reliable for future use, whether for ongoing research or large-scale production.

• Service We Offer

• Passage Stability Evaluation
  Our passage stability evaluation service involves regular monitoring of the strain's growth characteristics, morphology, and genetic profile after each passage. Creative Biolabs provides:
  • Passage monitoring to assess changes in growth rate, morphology, and other phenotypic characteristics.
  • Genetic analysis to detect any mutations, deletions, or other genetic variations that might impact strain performance.
  • Productivity testing to ensure that strains retain the ability to produce the desired products (e.g., proteins, metabolites) with consistent yields over time.
• Storage Stability Evaluation
  We offer comprehensive storage stability evaluations to determine the optimal storage conditions and ensure that strains remain viable, stable, and functional. Our services include:
  • Storage condition optimization: We evaluate various storage methods (e.g., cryopreservation, lyophilization, -80°C storage) to determine the most effective conditions for long-term strain preservation.
  • Long-term viability testing: Periodic viability assays are conducted to assess the recovery rate and overall health of stored strains.
  • Genetic stability testing: We monitor changes in genetic integrity during long-term storage to ensure that the strain remains genetically stable over time.
• Cryopreservation and Lyophilization Services
  To support long-term storage, we provide cryopreservation and lyophilization (freeze-drying) services that protect the strains from damage during freezing or dehydration. This ensures that strains can be preserved for extended periods without compromising their viability or stability. We work with clients to select the most suitable preservation method based on the strain type and intended application.
• Stability Protocol Development
  Creative Biolabs assists clients in developing tailored stability protocols for their specific strains. This includes recommendations for passage schedules, storage temperatures, and recovery methods to ensure that strains remain genetically stable and functional for the intended use.

• Service Workflow

• Technical Expertise

Our Strain Bank Passage & Storage Stability Evaluation service employs a variety of advanced techniques to assess and maintain strain stability:

• Microscopy and Imaging: We utilize advanced microscopy techniques to observe morphological changes in strains during passage and after storage, providing a clear view of any phenotypic variations.
• PCR and DNA Sequencing: To assess genetic stability, we use PCR and DNA sequencing technologies to identify mutations or genetic drift that may occur during passaging or storage.
• Viability Assays: We conduct cell viability assays (e.g., MTT assay, plate counting) to evaluate the health and recovery of stored strains.
• Cryopreservation and Lyophilization: State-of-the-art cryoprotectants and protocols maximize strain viability and genetic integrity during storage.

Contact Us

The Strain Bank Passage & Storage Stability Evaluation service is designed to ensure that your microbial or cell strains remain genetically stable, viable, and productive throughout their lifecycle. With our cutting-edge technologies and expert team, we provide reliable and reproducible results that you can count on for consistent performance in research, production, and therapeutic applications. Trust us to safeguard the quality of your strain collections, enabling their successful use for years to come. Contact us today to learn more about how we can assist you in maintaining the stability of your valuable biological resources.

For research use only. Not intended for any clinical use.