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αVβ3 integrin
Antibody-like Scaffold Protein Products
Recombinant Antibody Products
Functional Antibody Products
Formats
Anti-αVβ3 integrin Recombinant Antibody Products
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG2 - kappa
- Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: FC, IP, ELISA, Neut, FuncS, IF
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- Mouse Anti-αvβ3 Integrin Recombinant Antibody (clone D12) (HPAB-A1325-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, Inhib, FC
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- Human Anti-αvβ3 Integrin Recombinant Antibody (clone chD12) (HPAB-A1326-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, Inhib, FC
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- Human Anti-αvβ3 Integrin Recombinant Antibody (clone huD12) (HPAB-A1327-YJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib, FC
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- Human Anti-αvβ3 Integrin Recombinant Antibody (clone LM609); scFv Fragment (HPAB-1305WJ-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Human Anti-αvβ3 Integrin Recombinant Antibody (clone LM609); Fab Fragment (HPAB-1305WJ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
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- Scaffold Name: 10-FnIII
- Target: αvβ3 Integrin
- Species Reactivity: Human
- Derivation: Phage display
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- Scaffold Name: CTLA-4
- Target: αvβ3 integrin
- Species Reactivity: Human
- Derivation: Phage display
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For Research Use Only. Not For Clinical Use.
αVβ3 is a type of integrin that is a receptor for vitronectin. It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore, it is a receptor for phagocytosis on macrophages or dendritic cells. Integrin αVβ3 is potential drug target because abnormal expression of v3 is linked to the development and progression of various diseases. Inhibitors like etaracizumab may be used as antiangiogenics.
