


AFF4
Anti-AFF4 Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P, WB
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For Research Use Only. Not For Clinical Use.
Cancer-related genes, Disease related genes, Human disease related genes
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with ELL3; the interaction is direct (By similarity). Interacts with ELL2; the interaction is direct and leads to stabilize ELL2 and prevent ELL2 ubiquitination and degradation. Component of the super elongation complex (SEC), at least composed of EAF1, EAF2, CDK9, MLLT3/AF9, AFF (AFF1 or AFF4), the P-TEFb complex and ELL (ELL, ELL2 or ELL3). Interacts with ELL.