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AGTR2

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked cognitive disability. [provided by RefSeq, Jan 2010]
Protein class

G-protein coupled receptors

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Alveolar cells type 2)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Interacts with MTUS1.

Molecular function

G-protein coupled receptor, Receptor, Transducer

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