Anti-ALDH7A1 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs' Anti-ALDH7A1 Recombinant Antibodies leverage advanced recombinant engineering and proprietary validation protocols to deliver unmatched specificity and batch-to-batch consistency. Empower your studies in cancer metabolism, or mitochondrial dysfunction with tools that streamline target validation, reduce experimental variability, and accelerate translational outcomes.

ALDH7A1: A Critical Enzyme in Cellular Metabolism

ALDH7A1 serves as a crucial NAD^+- dependent enzyme, facilitating the oxidative deamination of intermediates in lysine catabolism. Its dysfunction is linked to pyridoxine-dependent epilepsy, cancer cell survival, and redox imbalance, making it a pivotal target for therapeutic and diagnostic innovation.

Alternative Names

Aldehyde dehydrogenase family 7 member A1; Antiquitin; ATQ1; PDE; ALDH-E1.

Background

The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]

Anti-ALDH7A1 rAb Products

Creative Biolabs' Anti-ALDH7A1 recombinant antibodies are engineered for high affinity and low cross-reactivity across species, validated in complex matrices like tumor lysates and cerebrospinal fluid. Optimized for ELISA, IHC, and flow cytometry, these antibodies enable precise detection of ALDH7A1 isoforms in neurodegenerative and oncology models.

Table.1 Featured anti-ALDH7A1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Every Anti-ALDH7A1 recombinant antibody undergoes rigorous specificity profiling. Lot-specific data packages ensure reproducibility in high-stakes applications, from biomarker quantification to preclinical efficacy studies.

Customer Reviews

rAb Production

Our scalable, serum-free mammalian expression platform ensures high-yield production of bioactive Anti-ALDH7A1 antibodies, with low endotoxin levels. From codon-optimized gene synthesis to purification, we guarantee seamless transition from research-scale to preclinical manufacturing.

Featured Anti-ALDH7A1 Recombinant Antibody Production Platforms
Fig.5 Recombinant anti-ALDH7A1 antibody synthesis at the milligram scale.

Fig.6 Gram-scale production of recombinant anti-ALDH7A1 antibodies.

rAb Modalities

Tailor your research with formats including Fab fragments, bispecifics, and fluorophore-conjugates. These modular designs support applications from live-cell imaging to cell targeting, adaptable to your experimental needs.

Fig.7 Approaches and modalities for producing full-length recombinant anti-ALDH7A1 antibodies.

With many years of expertise in cytoskeletal protein research, Creative Biolabs delivers rigorously validated tools to decode ALDH7A1's multifaceted roles. Contact our team today to discuss custom projects or request a product catalog.