ARSA

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-ARSA Recombinant Antibody Products

Hi-Affi™ Rabbit Anti-ARSA Recombinant Antibody (clone DS261AB) (MOR-0261)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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Hi-Affi™ Rabbit Anti-ARSA Recombinant Antibody (clone SI19DS) (MOR-3959)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.

Predicted to enable arylsulfatase activity and calcium ion binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in plasma membrane. Is integral component of membrane. Is expressed in brain and genitourinary system. Used to study metachromatic leukodystrophy. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy.

Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Plasma cells, Late spermatids, Proximal enterocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Karpas-707)

Interaction

Homodimer at neutral pH and homooctamer at acidic pH. Exists both as a single chain of 58 kDa (component A) or as a chain of 50 kDa (component B) linked by disulfide bond(s) to a 7 kDa chain (component C). Interacts with SUMF1.

Molecular function

Hydrolase

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