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BANK1
Anti-BANK1 Recombinant Antibody Products
- Rabbit Anti-BANK1 Antibody (MOB-0291MC)
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- Species Reactivity: Human
- Application: FACS, WB, ELISA
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1, 4, 5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Protein class
Disease related genes, Human disease related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (B-cells)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell)
Cell line specificity
Cell line enhanced (Daudi, HEL, HL-60, U-266/70)
Interaction
Interacts with LYN, ITPR1 and ITPR2.
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