BCRF1
Anti-BCRF1 Recombinant Antibody Products
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- Species Reactivity: EBV
- Type: IgG2b
- Application: Neut, WB
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For Research Use Only. Not For Clinical Use.
BCRF1 plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes which down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules and inhibiting IFN-gamma synthesis.