+ Filter
Loading...
Custom Services order now ship next day

BGLAP

Loading...

Anti-BGLAP Products

View More Products

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

For Research Use Only. Not For Clinical Use.


Background

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Protein class

FDA approved drug targets

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Sertoli cells, Ionocytes, Melanocytes, Plasma cells)

Immune cell specificity

Group enriched (NK-cell, plasmacytoid DC)

Cell line specificity

Cell line enhanced (hTERT-RPE1, U-87 MG)

More Types Infomation
Go to compare

Go to compare