FITC-A*02:01/Human BGLAP (YLYQWLGAPV) MHC Tetramer

CAT#: MHC-CN0435

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • BGLAP
  • Antigen Species
  • Human
  • Peptide
  • YLYQWLGAPV
  • Conjugate
  • FITC
  • Application
  • FCM, IHC

Target

  • Antigen Introduction
  • This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]
  • Alternative Names
  • Bone Gamma-Carboxyglutamate Protein; Gamma-Carboxyglutamic Acid-Containing Protein; Bone Gla Protein; Osteocalcin; BGP; Bone Gamma-Carboxyglutamate (Gla) Protein (Osteocalcin); Bone Gamma-Carboxyglutamate (Gla) Protein; OCN; OC;
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Protocol & Troubleshooting

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