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BMP8B
Anti-BMP8B Recombinant Antibody Products
- Mouse Anti-BMP8B Recombinant Antibody (clone 269809) (MOB-1499MZ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
Predicted location
Secreted
Single cell type specificity
Group enriched (Late spermatids, Early spermatids, Plasma cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (THP-1, U-266/70, U-266/84, WM-115)
Interaction
Homodimer; disulfide-linked.
Molecular function
Cytokine, Developmental protein, Growth factor
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