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CCNB2

Anti-CCNB2 Products
- Mouse Anti-CCNB2 Recombinant Antibody (clone 7C4) (MOB-2373CT)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P, IF, WB, FC
- Rabbit Anti-CCNB2 Recombinant Antibody (clone CBACN-163) (MRO-0412-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
- Mouse Anti-NHP CCNB2 Recombinant Antibody (clone X29.2) (VS-1024-XY147)
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- Species Reactivity: Human, Mouse, Non-human primate
- Type: Mouse IgG1
- Application: WB, IHC, IF, IP
- Anti-CCNB2 Immunohistochemistry Kit (VS-0325-XY335)
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- Species Reactivity: Human, Mouse, Rat
- Target: CCNB2
- Application: IHC
- Anti-Frog CCNB2 Immunohistochemistry Kit (VS-0525-XY1084)
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- Species Reactivity: Frog
- Target: CCNB2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
Protein class
Cancer-related genes, Plasma proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatocytes, Early spermatids, Extravillous trophoblasts, Erythroid cells, Cytotrophoblasts)
Immune cell specificity
Immune cell enriched (T-reg)
Cell line specificity
Low cell line specificity
Interaction
Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
Molecular function
Cyclin
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