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CFHR1

Anti-CFHR1 Products
- Mouse Anti-CFHR1 Recombinant Antibody (clone 5.1.5) (HPAB-0352-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, ELISA
- Mouse Anti-CFHR1 Recombinant Antibody (clone L20/3) (HPAB-0351-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, ELISA
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, WB, Neut, FuncS
- Mouse Anti-CFHR1 Recombinant Antibody (clone 5.1.5); scFv Fragment (HPAB-0352-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
- Mouse Anti-CFHR1 Recombinant Antibody (clone L20/3); scFv Fragment (HPAB-0351-YJ-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
- Mouse Anti-CFHR1 Recombinant Antibody (clone 5.1.5); Fab Fragment (HPAB-0352-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA
- Mouse Anti-CFHR1 Recombinant Antibody (clone L20/3); Fab Fragment (HPAB-0351-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC, ELISA
- Anti-CFHR1 Immunohistochemistry Kit (VS-0525-XY1395)
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- Species Reactivity: Human
- Target: CFHR1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, HeLa, HL-60, U-266/70)
Interaction
Head-to-tail homodimer and heterodimer with CFHR2 or CFHR5.
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