CHD4

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-CHD4 Recombinant Antibody Products

Hi-Affi™ Rabbit Anti-CHD4 Recombinant Antibody (clone DS686AB) (MOR-0686)
- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
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For Research Use Only. Not For Clinical Use.

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.