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CYP27B1

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For Research Use Only. Not For Clinical Use.


CYP27B1 (Cytochrome P450 Family 27 Subfamily B Member 1) is a Protein Coding gene. Diseases associated with CYP27B1 include Vitamin D Hydroxylation-Deficient Rickets, Type 1A and Hypocalcemic Vitamin D-Dependent Rickets. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. An important paralog of this gene is CYP27A1.
Protein class

Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets

Predicted location

Intracellular

Single cell type specificity

Group enriched (Proximal tubular cells, monocytes, Exocrine glandular cells)

Immune cell specificity

Immune cell enriched (MAIT T-cell)

Cell line specificity

Cell line enhanced (hTERT-HME1, RH-30)

Molecular function

Monooxygenase, Oxidoreductase

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