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DCTN4
Anti-DCTN4 Recombinant Antibody Products
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC-P
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For Research Use Only. Not For Clinical Use.
DCTN4 (Dynactin Subunit 4) is a Protein Coding gene. Diseases associated with DCTN4 include Cystic Fibrosis. Among its related pathways are COPI-independent Golgi-to-ER retrograde traffic and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include protein N-terminus binding.
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Member of the pointed-end complex of the dynactin shoulder complex which contains DCTN4, DCTN5 and DCTN6 subunits and ACTR10 (By similarity). Binds directly to the ACTR1A subunit of dynactin. Interacts with ATP7B, but not ATP7A, in a copper-dependent manner. Interacts with ANK2; this interaction is required for localization at costameres (By similarity).
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