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DGKH
Anti-DGKH Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the diacylglycerol kinase (DGK) enzyme family. Members of this family are involved in regulating intracellular concentrations of diacylglycerol and phosphatidic acid. Variation in this gene has been associated with bipolar disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2014]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Urothelial cells, Prostatic glandular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Interacts with RAF1 and BRAF. [Isoform 1]: Homooligomers (PubMed:12810723). Heterooligomers (PubMed:12810723). Oligomerization through the SAM domain inhibits the diacylglycerol kinase activity (PubMed:12810723). Heterooligomerizes with SAM domain-containing isoforms of DGKD (PubMed:12810723). [Isoform 2]: Does not form homooligomers.
Molecular function
Kinase, Transferase
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