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DOCK8
Loading...Anti-DOCK8 Products
- Anti-DOCK8 Immunohistochemistry Kit (VS-0525-XY2054)
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- Species Reactivity: Human
- Target: DOCK8
- Application: IHC
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- Anti-Mouse DOCK8 Immunohistochemistry Kit (VS-0525-XY2055)
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- Species Reactivity: Human, Mouse, Rat
- Target: DOCK8
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.