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DRD3
Anti-DRD3 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
DRD3 (Dopamine Receptor D3) is a Protein Coding gene. This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Diseases associated with DRD3 include Tremor, Hereditary Essential, 1 and Schizophrenia.
Protein class
Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Interacts with CLIC6 (By similarity). Interacts with GRK4 (PubMed:19520868). Interacts with PALM (PubMed:16386234). Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA (PubMed:26460884).
Molecular function
G-protein coupled receptor, Receptor, Transducer
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