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EMP2
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- Recombinant Anti-human EMP2 Antibody (MOB-317)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, Neut, FuncS
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- Human Anti-EMP2 Recombinant Antibody; scFv Fragment (TAB-334MZ-S(P)) (TAB-334MZ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; scFv Fragment (TAB-333MZ-S(P)) (TAB-333MZ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; scFv Fragment (TAB-332MZ-S(P)) (TAB-332MZ-S(P))
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- Species Reactivity: Mouse
- Type: Human scFv
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody (TAB-335MZ) (TAB-335MZ)
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- Species Reactivity: Mouse
- Type: Human IgG
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody (TAB-334MZ) (TAB-334MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody (TAB-333MZ) (TAB-333MZ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; Fab Fragment (TAB-335MZ-F(E)) (TAB-335MZ-F(E))
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- Species Reactivity: Mouse
- Type: Human Fab
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; Fab Fragment (TAB-334MZ-F(E)) (TAB-334MZ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; Fab Fragment (TAB-333MZ-F(E)) (TAB-333MZ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; Fab Fragment (TAB-332MZ-F(E)) (TAB-332MZ-F(E))
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- Species Reactivity: Mouse
- Type: Human Fab
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody; scFv Fragment (TAB-335MZ-S(P)) (TAB-335MZ-S(P))
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- Species Reactivity: Mouse
- Type: Human scFv
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody (TAB-332MZ) (TAB-332MZ)
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- Species Reactivity: Mouse
- Type: Human IgG
- Application: FC
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- Human Anti-EMP2 Recombinant Antibody (TAB-231CL) (TAB-231CL)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Recombinant Anti-human EMP2 Antibody scFv Fragment (MOB-317-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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- Recombinant Anti-human EMP2 Antibody Fab Fragment (MOB-317-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, IF, FuncS
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For Research Use Only. Not For Clinical Use.
Enables integrin binding activity. Involved in several processes, including early endosome to late endosome transport; embryonic process involved in female pregnancy; and protein localization to cell surface. Acts upstream of or within positive regulation of integrin-mediated signaling pathway. Located in Golgi apparatus; apical plasma membrane; and cell surface. Colocalizes with cytoplasmic vesicle; membrane raft; and plasma membrane. Is expressed in several structures, including alimentary system; endometrium; medulla oblongata lateral wall; respiratory system; and sensory organ. Used to study placental insufficiency. Human ortholog(s) of this gene implicated in nephrotic syndrome type 10. Orthologous to human EMP2 (epithelial membrane protein 2).
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Group enriched (Alveolar cells type 1, Suprabasal keratinocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (MCF7, RT4, SK-BR-3, T-47d)
Interaction
Interacts with PTK2; regulates PTK2 activation and localization (PubMed:19494199, 21637765). Interacts with ITGB3; regulates the levels of the heterodimer ITGA5-ITGB3 integrin surface expression (PubMed:16216233). Interacts with P2RX7 (via C-terminus) (PubMed:12107182). Interacts with ITGB1; the interaction may be direct or indirect and ITGB1 has a heterodimer form.
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