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EMP2

Protein class

Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Group enriched (Alveolar cells type 1, Suprabasal keratinocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (MCF7, RT4, SK-BR-3, T-47d)

Interaction

Interacts with PTK2; regulates PTK2 activation and localization (PubMed:19494199, 21637765). Interacts with ITGB3; regulates the levels of the heterodimer ITGA5-ITGB3 integrin surface expression (PubMed:16216233). Interacts with P2RX7 (via C-terminus) (PubMed:12107182). Interacts with ITGB1; the interaction may be direct or indirect and ITGB1 has a heterodimer form.

More Types Infomation

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