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EPB41
Anti-EPB41 Recombinant Antibody Products
- Recombinant Mouse Anti-Human EPB41 Antibody (MOB-1392MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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- Anti-EPB41 Immunohistochemistry Kit (VS-0325-XY770)
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- Species Reactivity: Human, Mouse, Rat
- Target: EPB41
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Protein class
Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Erythroid cells, Rod photoreceptor cells, Bipolar cells, Cone photoreceptor cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HEL, K-562)
Interaction
Binds with a high affinity to glycophorin and with lower affinity to band III protein. Associates with the nuclear mitotic apparatus. Interacts with calmodulin (PubMed:10692436). Interacts with CENPJ (PubMed:11003675). Interacts with DLG1 (PubMed:7937897). Also found to associate with contractile apparatus and tight junctions. Interacts with NUMA1; this interaction is negatively regulated by CDK1 during metaphase and promotes anaphase-specific localization of NUMA1 in symmetrically dividing cells (PubMed:23870127). Interacts with ATP2B1; regulates small intestinal calcium absorption through regulation of membrane expression of ATP2B1 (By similarity).
Molecular function
Actin-binding, Calmodulin-binding
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