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EVL
Anti-EVL Recombinant Antibody Products
- Recombinant Mouse Anti-Human EVL Antibody (MOB-0745MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
EVL (Enah/Vasp-Like) is a Protein Coding gene. Diseases associated with EVL include vein disease and splenic abscess. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. GO annotations related to this gene include actin binding and profilin binding. An important paralog of this gene is SPRED1.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (NK-cells, Rod photoreceptor cells, Cone photoreceptor cells, T-cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (MOLT-4)
Interaction
Homotetramer (By similarity). Binds to the SH3 domains of ABL1, LYN and SRC. Also binds to profilin, with preference for isoform IIa of PFN2, and the WW domain of APBB1/FE65. Binds to SEMA6A. Interacts, via the Pro-rich region, with the C-terminal SH3 domain of DNMBP. Interacts with RAPH1. Binds, via the EVH1 domain, the Pro-rich domain of Listeria monocytogenes actA (By similarity). Binds, via the EVH1 domain, the Pro-rich domain of ZYX. Interacts with FYB1 (PubMed:10747096). Interacts with ZDHHC17 (PubMed:28882895).
Molecular function
Actin-binding
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