FANCB

Formats

Anti-FANCB Recombinant Antibody Products

Mouse Anti-FANCB Recombinant Antibody (clone 36A10) (MOB-2183z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IHC
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Rabbit Anti-FANCB Recombinant Antibody (clone R05-8B7) (VS3-FY1714)
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of the Fanconi anemia complementation group B. This protein is assembled into a nucleoprotein complex that is involved in the repair of DNA lesions. Mutations in this gene can cause chromosome instability and VACTERL syndrome with hydrocephalus.

Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Extravillous trophoblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Low cell line specificity

Interaction

Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients.

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