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Gag p24
Anti-Gag p24 Recombinant Antibody Products
- A*11:01/HIV Gag p24 (ACQGVGGPGHK) MHC Pentamer (MHC-YF449)
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- Class: Class I
- Antigen: Gag p24
- Antigen Species: HIV
- Peptide: ACQGVGGPGHK
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- B*08:01/HIV Gag p24 (EIYKRWII) MHC Pentamer (MHC-YF450)
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- Class: Class I
- Antigen: Gag p24
- Antigen Species: HIV
- Peptide: EIYKRWII
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- B*08:01/HIV Gag p24 (GEIYKRWII) MHC Pentamer (MHC-YF451)
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- Class: Class I
- Antigen: Gag p24
- Antigen Species: HIV
- Peptide: GEIYKRWII
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- B*27:05/HIV Gag p24 (KRWIILGLNK) MHC Pentamer (MHC-YF452)
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- Class: Class I
- Antigen: Gag p24
- Antigen Species: HIV
- Peptide: KRWIILGLNK
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- B*27:05/HIV Gag p24 (KRWIIMGLNK) MHC Pentamer (MHC-YF453)
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- Class: Class I
- Antigen: Gag p24
- Antigen Species: HIV
- Peptide: KRWIIMGLNK
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- H-2Kd/HIV Gag p24 (AMQMLKETI) MHC Pentamer (MHC-YF454)
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- Class: Class I
- Antigen: Gag p24
- Antigen Species: HIV
- Peptide: AMQMLKETI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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For Research Use Only. Not For Clinical Use.
Capsid protein p24: Forms the conical core that encapsulates the genomic RNA-nucleocapsid complex in the virion. Most core are conical, with only 7% tubular. The core is constituted by capsid protein hexamer subunits. The core is disassembled soon after virion entry. Host restriction factors such as monkey TRIM5-alpha or TRIMCyp bind retroviral capsids and cause premature capsid disassembly, leading to blocks in reverse transcription. Capsid restriction by TRIM5 is one of the factors which restricts HIV-1 to the human species. Host PIN1 apparently facilitates the virion uncoating (By similarity). On the other hand, interactions with PDZD8 or CYPA stabilize the capsid (PubMed:24554657).