HCV-E2
Anti-HCV-E2 Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
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For Research Use Only. Not For Clinical Use.
Hepatitis C E2 is a virus envelope glycoprotein which forms a heterodimer with the E1 protein. E2 inhibits human EIF2AK2/PKR activation, preventing the establishment of an antiviral state. E2 is a viral ligand for CD209/DCSIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells (DCs), and on liver sinusoidal endothelial cells and macrophage-like cells of lymph node sinuses.