IGL
Anti-IGL Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: FC, IF, IHC, WB
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- Species Reactivity: Catfish
- Type: Mouse IgG2b, κ
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse IgG3, κ
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse IgG3, κ
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse IgG1, κ
- Application: IF, FC
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- Species Reactivity: Catfish
- Type: Mouse IgG2b, κ
- Application: WB, IP, FC
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- Species Reactivity: Catfish
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- Species Reactivity: Catfish
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- Species Reactivity: Catfish
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- Species Reactivity: Catfish
- Type: Mouse scFv
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse scFv
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse scFv
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse scFv
- Application: IF
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- Species Reactivity: Catfish
- Type: Mouse scFv
- Application: WB, IP, FC
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- Species Reactivity: Catfish
- Type: Mouse Fab
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse Fab
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse Fab
- Application: WB, ELISA, FC
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- Species Reactivity: Catfish
- Type: Mouse Fab
- Application: IF
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- Species Reactivity: Catfish
- Type: Mouse Fab
- Application: WB, IP, FC
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For Research Use Only. Not For Clinical Use.
Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species.