ING2

AbPlus Recombinant Antibody Products

Anti-ING2 Recombinant Antibody Products

Anti-ING2 Immunohistochemistry Kit (VS-0325-XY1127)
- Species Reactivity: Human, Mouse
- Target: ING2
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. Alternative splicing results in multiple transcript variants.

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts with H3K4me3 and to a lesser extent with H3K4me2. Component of a mSin3A-like complex at least consisting of SIN3A, HDAC1, HDAC2, RBBP4/RbAp48, RBBP7/RbAp46, SAP30 and ING2.

Molecular function

Chromatin regulator

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