JUP

AbPlus Formats

Anti-JUP Recombinant Antibody Products

Mouse Anti-JUP Recombinant Antibody (clone 36A6) (MOB-2482z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, ICC, IF, IHC
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Recombinant Mouse anti-Human JUP Monoclonal antibody (Nvod24) (MOB-2444CT)
- Species Reactivity: Human
- Application: ICC/IF, FC, WB, IP
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Recombinant Rabbit Anti-JUP Monoclonal Antibody (JF0973) (MRO-0624-CN)
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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Mouse Anti-JUP Recombinant Antibody (ZG-0366F) (ZG-0366F)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, IF, ELISA
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Mouse Anti-JUP Recombinant Antibody (clone 606CT21.5.1) (VS3-QX624)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG3
- Application: WB
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Mouse Anti-JUP Recombinant Antibody (clone 4B4-C7-E9) (VS3-QX625)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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Rabbit Anti-JUP Recombinant Antibody (clone JF0973) (VS3-WK405)
- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, FC
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Recombinant Rabbit Anti-JUP Antibody (clone R05-0C2) (VS3-FY788)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF
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Rabbit Anti-JUP Recombinant Antibody (clone R01-3P1) (VS3-XY3403)
- Species Reactivity: Human, Mouse, Rat, Dog
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF, FC
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Anti-JUP Immunohistochemistry Kit (VS-0325-XY1170)
- Species Reactivity: Human, Mouse, Rat
- Target: JUP
- Application: IHC
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Mouse Anti-JUP Monoclonal Antibody (clone 4C12) (VS7-0425-WR173)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC
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For Research Use Only. Not For Clinical Use.

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Suprabasal keratinocytes, Pancreatic endocrine cells, Squamous epithelial cells, Distal enterocytes)

Immune cell specificity

Group enriched (non-classical monocyte, eosinophil, intermediate monocyte, myeloid DC, memory B-cell, classical monocyte, naive B-cell)

Cell line specificity

Cell line enhanced (HaCaT, OE19)

Interaction

Homodimer. Component of an E-cadherin/catenin adhesion complex composed of at least E-cadherin/CDH1 and gamma-catenin/JUP, and possibly alpha-catenin/CTNNA1; the complex is located to adherens junctions. The stable association of CTNNA1 is controversial as CTNNA1 was shown not to bind to F-actin when assembled in the complex. Interacts with MUC1. Interacts with CAV1 (By similarity). Interacts with PTPRJ. Interacts with DSG1. Interacts with DSC1 and DSC2. Interacts with PKP2.

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