


KCNH1

Anti-KCNH1 Products
- Anti-Human KCNH1 Recombinant Antibody (TAB-467CL)
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- Derivation: Human
- Species Reactivity: Human
- Type: Antibody
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- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Mouse Anti-KCNH1 Recombinant Antibody (clone ImAB5) (HPAB-1773-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: Inhib
- Human Anti-KCNH1 Antibody, mRNA (TAB-467CL-mRNA)
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- Species Reactivity: Human
- Mouse Anti-KCNH1 Recombinant Antibody (clone ImAB5); scFv Fragment (HPAB-1773-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib, IF, IHC
- Mouse Anti-KCNH1 Recombinant Antibody (clone ImAB5); Fab Fragment (HPAB-1773-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Inhib, IF, IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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- Species Reactivity: Human
- Target: KCNH1
- Host Animal: Mouse
- Application: ELISA, FC, Inhib, Cell-uptake
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For Research Use Only. Not For Clinical Use.
Background
Disease related genes, Human disease related genes, Potential drug targets, Transporters, Voltage-gated ion channels
Intracellular, Membrane (different isoforms)
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Oligodendrocytes)
Not detected in immune cells
Cell line enhanced (LHCN-M2, RH-30, RPTEC TERT1, SH-SY5Y, SK-MEL-30, T-47d)
The potassium channel is composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH5/EAG2 (PubMed:11943152). Interacts with ALG10B (By similarity). Interacts with RABEP1 (By similarity). Interacts (via C-terminus) with CTTN (PubMed:23144454). Interacts (via C-terminal cytoplasmic region) with Ca(2+)-bound calmodulin (PubMed:10880439, PubMed:27325704, PubMed:27618660). Interacts with the spider kappa-theraphotoxin-Aa1a and mu/kappa-theraphotoxin-Ap1a (PubMed:30149017).
Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel