Afuco™ Anti-Human KCNH1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-448CL)
Anti-KCNH1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody which specifically binds to/interacts with EAG1 ion channel can be used for the treatment of a hyperproliferative disease, inflammatory disease, psoriasis, or a neurodegenerative disease.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14551/1585_A3_4_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14551/1585_A3_4_selected.jpg
Figure 2 High expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_B_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_B_9_5_val_selected.jpg
Figure 3 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_A_9_4_val_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_B_8_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_B_8_5.jpg
Figure 5 Colon
(Enterocytes - Peripheral nerve/ganglion Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_A_8_3.jpg
(Enterocytes - Peripheral nerve/ganglion Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_A_8_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (LHCN-M2, RH-30, RPTEC TERT1, SH-SY5Y, SK-MEL-30, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143473-KCNH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143473-KCNH1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- KCNH1; potassium channel, voltage gated eag related subfamily H, member 1; EAG; EAG1; h-eag; Kv10.1; potassium voltage-gated channel subfamily H member 1; hEAG1; EAG channel 1; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; voltage-gated potassium channel subunit Kv10.1; potassium voltage-gated channel, subfamily H (eag-related), member 1
- Gene ID
- 3756
- UniProt ID
- O95259
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1914 | Hi-Affi™ Recombinant Rabbit Anti-KCNH1 Monoclonal Antibody (DS1914AB) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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