Afuco™ Anti-Human KCNH1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-448CL)
Anti-KCNH1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibody which specifically binds to/interacts with EAG1 ion channel can be used for the treatment of a hyperproliferative disease, inflammatory disease, psoriasis, or a neurodegenerative disease.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14551/1585_A3_4_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14551/1585_A3_4_selected.jpg
Figure 2 High expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_B_9_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_B_9_5_val_selected.jpg
Figure 3 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_A_9_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19445/153533_A_9_4_val_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_B_8_5.jpg
(Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_B_8_5.jpg
Figure 5 Colon
(Enterocytes - Peripheral nerve/ganglion Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_A_8_3.jpg
(Enterocytes - Peripheral nerve/ganglion Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/76421/168968_A_8_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (LHCN-M2, RH-30, RPTEC TERT1, SH-SY5Y, SK-MEL-30, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143473-KCNH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143473-KCNH1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Inflammatory Diseases
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- KCNH1; potassium channel, voltage gated eag related subfamily H, member 1; EAG; EAG1; h-eag; Kv10.1; potassium voltage-gated channel subfamily H member 1; hEAG1; EAG channel 1; ether-a-go-go potassium channel 1; ether-a-go-go, Drosophila, homolog of; voltage-gated potassium channel subunit Kv10.1; potassium voltage-gated channel, subfamily H (eag-related), member 1
- Gene ID
- 3756
- UniProt ID
- O95259
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1914 | Hi-Affi™ Recombinant Rabbit Anti-KCNH1 Monoclonal Antibody (DS1914AB) | WB | IgG |
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