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LIPA
Anti-LIPA Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IF, IHC, IP
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- Mouse Anti-LIPA Monoclonal Antibody (clone 9G7F12) (VS7-0425-WR278)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, ELISA
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For Research Use Only. Not For Clinical Use.
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Kupffer cells, Hofbauer cells, Macrophages)
Immune cell specificity
Group enriched (intermediate monocyte, non-classical monocyte, classical monocyte, myeloid DC)
Cell line specificity
Cell line enhanced (A-431, AN3-CA, ASC TERT1)
Interaction
Monomer.
Molecular function
Hydrolase
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