Anti-MAOA Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Are prolonged development cycles and inconsistent antibody performance hindering your neuropharmacology research? Creative Biolabs' anti-MAOA recombinant antibodies leverage advanced recombinant engineering and stringent validation protocols to deliver unmatched specificity and reproducibility. These tools streamline target validation, reduce optimization time, and empower robust data generation for preclinical development.

MAOA: A Critical Regulator of Neurotransmitter Homeostasis

Amine oxidase [flavin-containing] A (MAOA) is a mitochondrial enzyme pivotal in catalyzing the oxidative deamination of monoamine neurotransmitters, including serotonin, norepinephrine, and dopamine. Dysregulated MAOA activity is implicated in depression, aggression, and neurodegenerative disorders, making it a high-value therapeutic and diagnostic target.

Alternative Names

MAO-A; MAOA; Monoamine oxidase A; Amine oxidase [flavin-containing] A.

Background

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Protein class

Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Proximal tubular cells, Undifferentiated cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC diff, HHSteC, HSkMC, hTCEpi, RT4)

Interaction

Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

Molecular function

Oxidoreductase

More Types Infomation

Anti-MAOA rAb Products

Creative Biolabs' anti-MAOA recombinant antibodies are engineered for high-affinity binding across human and model species. Optimized for functional assays, IHC, and therapeutic target screening, these biologics enable precise interrogation of MAOA-mediated pathways in neurological and oncological research.

Cat. No. Product Name Target Species Host Species Applications
MOB-2125z Mouse Anti-MAOA Recombinant Antibody (clone 2G1) Human Mouse WB, IHC
VS3-FY874 Recombinant Rabbit Anti-MAOA Antibody (clone R07-9I3) Human, Mouse, Rat Rabbit IgG WB, IHC-P
ZG-0109U Rabbit Anti-MAOA Recombinant Antibody (clone 4C11) Human Rabbit IgG ELISA, IHC, IF
MRO-2040-CN Rabbit Anti-MAOA Polyclonal Antibody (MRO-2040-CN) Human Rabbit IgG WB, IHC
MRO-0960-C Recombinant Mouse Anti-MAOA Monoclonal Antibody (5D1) Human Mouse WB, IF

Table.1 Featured anti-MAOA recombinant antibody product at Creative Biolabs.

Creative Quality Control

Each anti-MAOA recombinant antibody undergoes rigorous validation via ELISA, Western blot, and functional inhibition assays. Lot-to-lot consistency is ensured through mass spectrometry profiling and kinetic binding analysis (SPR), guaranteeing reliable performance in complex biological matrices.

IF analysis. (Creative Biolabs Original)Fig.1 IF analysis of anti-MAOA antibody.
(Cat# MOB-2125z, Creative Biolabs).

WB staining. (Creative Biolabs Original)Fig.2 WB result of anti-MAOA antibody.
(Cat# VS3-FY874, Creative Biolabs).

IHC analysis. (Creative Biolabs Original)Fig.3 IHC results of anti-MAOA antibody.
(Cat# VS3-FY874, Creative Biolabs).

IHC staining. (Creative Biolabs Original)Fig.4 IHC staining result of anti-MAOA antibody.
(Cat# ZG-0109U, Creative Biolabs).

Customer Reviews

Excellent
Qi**n*
Mouse Anti-MAOA Recombinant Antibody (clone 2G1)
The anti-MAOA antibody (Cat#: MOB-2125z) exhibited exceptional specificity in our serotonin degradation studies, eliminating cross-reactivity with MAOB. This reliability was critical for validating novel inhibitors in depression models.
12/Jan/2024
Excellent
Che**g*
Rabbit Anti-MAOA Polyclonal Antibody (MRO-2040-CN)
Using Creative Biolabs' anti-MAOA (MRO-2040-CN) for IHC in post-mortem brain tissues provided unprecedented clarity in mapping enzyme distribution across neuronal subtypes.
03/Mar/2024
Excellent
An***i
Rabbit Anti-MAOA Recombinant Antibody (clone 4C11)
The antibody's low batch variability (Cat#: ZG-0109U) saved months of optimization in our drug screening workflow. Consistent results across 15+ assays accelerated candidate prioritization.
2/May/2024

rAb Production

Our chemically defined mammalian expression platform enables accurate post-translational processing and supports production scalability from milligram to gram quantities. By coupling AI-assisted codon optimization with state-of-the-art perfusion bioreactor systems, we consistently attain >95% monomeric purity—crucial for both in vivo applications and diagnostic reliability.

Featured Anti-MAOA Recombinant Antibody Production PlatformsMilligram-scale. (Creative Biolabs Original)
Fig.5 Production of recombinant anti-MAOA antibodies at milligram scale.

Gram-scale. (Creative Biolabs Original)Fig.6 Gram-level expression of MAOA-directed recombinant antibodies.

rAb Modalities

Customize your research with formats spanning scFv, bispecific antibodies, and Fc-engineered variants. These modalities support diverse applications, including live-cell imaging, multi-omics profiling, and in vivo therapeutic efficacy studies.

MAOA antibody production and modalities. (Creative Biolabs Original)Fig.7 Approaches for the generation of full-length recombinant antibodies against MAOA.

Creative Biolabs bolsters your research by supplying premium anti‑MAOA recombinant antibodies, underpinned by our relentless pursuit of scientific innovation and unwavering commitment to client success. For inquiries or bespoke project consultations, please reach out—our team of experts stands ready to empower your investigative goals.

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