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MPIG6B

Anti-MPIG6B Products
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA
- Human Anti-MPIG6B Recombinant Antibody (clone AB174); scFv Fragment (PABJ-0148-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-MPIG6B Recombinant Antibody (clone AB174); Fab Fragment (PABJ-0148-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Target: MPIG6B
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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For Research Use Only. Not For Clinical Use.
This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (granulocytes)
Immune cell specificity
Immune cell enhanced (NK-cell)
Cell line specificity
Cell line enriched (HEL)
Interaction
Interacts (via ITIM motif) with PTPN6 and PTPN11 (PubMed:11544253, PubMed:23112346). Binds to heparin (PubMed:15848171).
Molecular function
Heparin-binding, Receptor
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