MSN

Antibody Magnetic Beads AbPlus Recombinant Antibody Products Formats

Anti-MSN Recombinant Antibody Products

AbPlus™ Anti-MSN Magnetic Beads (VS-0724-YC249) (VS-0724-YC249)
- Target: MSN
- Target Species: Human
- Application: IP, Protein Purification
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Anti-MSN Immunohistochemistry Kit (VS-0325-XY1380)
- Species Reactivity: Human, Mouse, Rat
- Target: MSN
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

Protein class

Cancer-related genes, Disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (NK-cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation. Interacts with SLC9A3R1 (PubMed:9314537, PubMed:15020681). Interacts with PPP1R16B (PubMed:18586956). Interacts with PDZD8. Interacts with SELPLG and SYK; these interaction mediate the activation of SYK by SELPLG (PubMed:12387735). Interacts with PDPN (via cytoplasmic domain); this interaction activates RHOA and promotes epithelial-mesenchymal transition (PubMed:17046996). Interacts with SPN/CD43 cytoplasmic tail (PubMed:9616160, PubMed:11728332). Interacts with CD44 (PubMed:9298994). Interacts with ICAM2 (By similarity). Interacts with ICAM3 (via C-terminus) (PubMed:9298994). Interacts with PDZD8 (PubMed:21549406). Interacts with F-actin (PubMed:10212266). Interacts with CD46 (PubMed:7884872). Interacts with PTPN6 (By similarity). (Microbial infection) Interacts with HIV-1 envelope protein gp120.

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