NKD2

Formats

Anti-NKD2 Recombinant Antibody Products

Recombinant Mouse anti-Human NKD2 Monoclonal antibody (MOB-0223CT)
- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.

This gene encodes a member of a family of proteins that function as negative regulators of Wnt receptor signaling through interaction with Dishevelled family members. The encoded protein participates in the delivery of transforming growth factor alpha-containing vesicles to the cell membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Fibroblasts, Spermatogonia, Microglial cells, Melanocytes, Langerhans cells, Muller glia cells, Endometrial stromal cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BEWO, HEK93, MOLT-4, NB-4, REH, RPMI-8226)

Interaction

Interacts with DVL1, DVL2, DVL3 and PPP2R3A (By similarity). Interacts with RNF25 and TGFA (via cytoplasmic domain).

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