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NPSR1
Anti-NPSR1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Protein class
Disease related genes, G-protein coupled receptors, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Early spermatids, Excitatory neurons, Inhibitory neurons, Late spermatids, Cardiomyocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HAP1)
Molecular function
G-protein coupled receptor, Receptor, Transducer
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