Anti-OAS1 Recombinant Antibody Products

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Anti-OAS1 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs provides premium-grade recombinant antibodies specifically developed against OAS1, engineered to accelerate discoveries in life science research. Leveraging cutting-edge production methodologies and stringent quality control measures, we guarantee antibodies that exceed industry standards for specificity and reproducibility. Researchers benefit from our comprehensive collection of meticulously validated antibodies, each delivering exceptional experimental performance and scientific utility. Beyond supplying these innovative biological tools, our specialists offer personalized consultation services to optimize study design and implementation. Partnering with us ensures access to scientifically validated antibody solutions backed by a team genuinely committed to advancing your research objectives.

OAS1: A Promising Target in Viral Infections Autoimmune Disorders and Cancer

OAS1 is an interferon-induced enzyme involved in the antiviral response by activating RNase L, which degrades viral RNA and inhibits replication. Its activity is crucial in controlling infections such as hepatitis C, West Nile virus, and SARS-CoV-2. Genetic variations in OAS1 have been associated with different responses to viral infections, influencing susceptibility and disease severity, particularly in COVID-19 cases. In addition to its antiviral role, OAS1 is linked to autoimmune conditions like systemic lupus erythematosus, where abnormal expression may contribute to immune system dysregulation. Recent evidence also points to its potential involvement in cancer, where altered OAS1 signaling might affect immune surveillance and tumor progression. As a result, OAS1 is increasingly recognized as an important biomarker and therapeutic target in both infectious and immune-mediated diseases.

Alternative Names

Complement OAS1; 2-5 Oligoadenylate Synthetase 1 P48 Isoform; EC 2.7.7; IFI-4; (2-5)Oligo(A) Synthase 1; 2-5 Oligoadenylate Synthetase 1 P52 Isoform; EC 2.7.7.84; 2,5-Oligoadenylate Synthetase 1 (40-46 KD); 2,5-Oligo A Synthetase 1; 2-5A Synthetase 1; 2-5-Oligoisoad

Background

Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2-5-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.

Anti-OAS1 rAb Products

Our objective is to expedite scientific discovery by offering high-quality anti-OAS1 recombinant antibodies that merge robust performance, reliable value, and dedicated technical support, all strategically designed to assist your research at each and every stage of its progression.

Table 1. Featured anti-OAS1 recombinant antibody products at Creative Biolabs.

Customer Reviews

Excellent

Al**r
Mouse Anti-OAS1 Recombinant Antibody (clone 43G5) (CAT#: MOB-2813z)

We tested the Mouse Anti-OAS1 Recombinant Antibody in Western blot using lysates from A549 and HeLa cells. The antibody produced a clear, specific band with low background. It worked well under standard conditions and didn’t require much optimization. Overall, it performed reliably in our WB assays.

11/Jan/2024

Excellent

N**ie
Recombinant Mouse anti-Human OAS1 Monoclonal antibody (EML725)

In our immunofluorescence experiments, we used the Recombinant Mouse anti-Human OAS1 Monoclonal Antibody (EML725) on Huh7 cells. The staining was clean and specific, with good signal intensity and minimal background. It fit well into our existing IF workflow and gave reproducible results. A useful antibody for visualizing OAS1 expression.

15/Apr/2024

rAb Production

Drawing upon decades of specialized expertise in antibody engineering and optimization, we consistently provide rigorously validated recombinant antibodies with rapid delivery timelines. Our customer-focused approach combines dependable product performance with responsive support, ensuring researchers receive precisely tailored solutions to accelerate their scientific investigations without compromising quality standards.

Featured Anti-OAS1 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale recombinant antibody production.

Fig.2 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs is dedicated to offering researchers a broad spectrum of top-tier recombinant antibodies across various formats, showcasing our proficiency in diverse antibody engineering methodologies that enable the delivery of versatile and impactful solutions. Every product in our portfolio is complemented by customizable services carefully tailored to address the unique and specific requirements of your research projects, ensuring alignment with your scientific objectives at every stage.

Fig.3 Full Length Anti-OAS1 Recombinant Antibody Production and Modalities.

If you need more information about the OAS1 target, please don't hesitate to contact us via phone or email. Our experienced team is always available to help with any questions or experimental challenges, ensuring you have the guidance and support necessary for successful research outcomes.